Voltaire makes various allusions to the New World in a passage in which Professor Pangloss explains that his syphilis infection originated in Christopher Columbus’s voyage to the Americas. The passage is also an example of situational irony:
“[It] was a thing unavoidable, a necessary ingredient in the best of worlds; for if Columbus had not in an island of America caught this disease, which contaminates the source of life, frequently even hinders generation, and which is evidently opposed to the great end of nature, we should have neither chocolate nor cochineal. We are also to observe that upon our continent, this distemper is like religious controversy, confined to a particular spot. The Turks, the Indians, the Persians, the Chinese, the Siamese, the Japanese, know nothing of it [...]
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